About megatomi.com
About megatomi.com
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Our new Apparent+ tissue clearing technique is the sole approach that delipidates samples without improve in morphology and with minimal impact on structural integrity.
Megatome can be a vibrating microtome built to portion a wide range of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome allows large-throughput tissue sectioning with uniform floor profile, along with nominal tissue problems and information reduction.
Antibodies may well choose weeks to diffuse through only a few millimeters of tissue, with a steep labeling gradient from surface to Main.
Megatome is designed for accuracy: the blade vibrates at a greater frequency and larger amplitude assortment than other microtomes, and includes a special deflection Handle mechanism.
SE works by using a rotational electric powered discipline to disperse very electromobile molecules (including antibodies or surfactant micelles) all through a porous sample with out harming electrically billed constructions inside the tissue. This enables 2-four working day clearing of intact organs,
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Megatome can be a novel microtome that allows for top-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with nominal tissue harm and knowledge reduction.
It’s time for you to upgrade your microtome to Megatome. With precise high-frequency slicing for an unmatched variety of sample sizes and kinds – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied apps.
Absolutely delipidate entire mouse brains or comparably sized samples in only one day with SmartBatch+, or in a single week with our passive clearing kit.
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Leverage the Distinct+ tissue clearing approach, in conjunction with eFLASH and patented stochastic electrotransport systems, to rapidly very clear and label complete organs. Critical highlights and options consist of:
Our novel Defend tissue preservation strategy varieties intramolecular bonds using polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.